SCN5A and atrial fibrillation: The main entities related to SCN5A mutations include an autosomal dominant form of the LQTS (LQT3; Wang et al., 1995), BS (Probst et al., 2003), progressive cardiac conduction disease (CCD; Scott et al., 1999), sinus node dysfunction (SND; Benson et al., 2003), AF (Olson et al., 2005; Darbar et al., 2008), atrial standstill (Tan, 2006; Remme et al., 2008), and dilated cardiomyopathy (DCM; McNair et al., 2004).