Our identification of GAG-modified APLP2 and APLP2 C-terminal fragment expression in pancreatic cancer cell lines did not clarify whether these forms of APLP2 occur only in the transformed state, or if GAG-APLP2 and APLP2 C-terminal fragments are also endogenously present in untransformed pancreatic ductal cells. This evidence concerns the gene APLP2 and pancreatic neoplasm.