DMKN and colorectal cancer: Research on new screening methods for the early diagnosis of colorectal cancer has been performed around the world, and the methylation of serum NEUROG1 [25], the serum dermokine level [26], and serum hydroxylated polyunsaturated ultra-long-chain fatty acid levels [27] have been demonstrated to be serum biomarker candidates for the early detection of colorectal cancer.