For instance, MSLN expression (1+ or greater) was observed in 71% of patients with PDA in the present study (as compared to 85–100% in prior studies [32], [35]) and MUC4 expression (1+ or greater) was observed in 55% (as compared to 90% in prior studies [36], [37]). The gene discussed is MSLN; the disease is Patent ductus arteriosus.