CXCR3 and hepatitis C virus infection: In hepatitis C the CXC-chemokine receptor CXCR3 and its ligands (CXCL9, CXCL10, CXCL11) have gained specific attention because various studies demonstrated elevated levels of CXCR3 ligand CXCL10 to be predictive of the failure to response to HCV therapy [1]–[4] and to be associated with stage of fibrosis [4]–[10].