In the present study, we identified rs2009066 to be the SNP most significantly associated with high myopia, and this SNP is located 3 kb downstream of CRYBA4. Based on an online tool for SNP function prediction (SNPinfo; http://manticore.niehs.nih.gov/snpfunc.htm), rs2009066 does not seem to have any predicted functional role. The gene discussed is CRYBA4; the disease is myopia.