To our knowledge, there have been no prior reports of null associations of KDR-604, PPARD-87, PPARGC1A Gly482Ser, TNFRSF1A-329, ADIPOQ+45, ADIPOQ-11426, IL6ST Gly148Arg, IL6-6331, and TNF-863 functional SNPs with prostate cancer. This evidence concerns the gene IL6 and Familial prostate cancer.