TLR2 and chlamydia trachomatis infectious disease: For instance, M. bovis BCG [3], but not the non-pathogenic bacteria Mycobacterium smegmatis or Bacillus subtilis[3], induces toll-like receptor 2 (TLR2)-mediated formation of LBs in macrophages; TLR6 but not TLR2 drives LB biogenesis in M. leprae-infected Schwann cells [53], and TLR2 but not TLR4 are involved in the formation of LBs in macrophages infected with Chlamydia pneumonia[15].