Hemoglobin (Hb) levels dropped from an average of 12.5 g/dL in control mice to an average of 7.5 g/dL in DOX-treated mice, and lymphocyte counts were significantly reduced in Doxil®-treated animals, indicating both anemia and severe lymphocytopenia (Fig. 3d). This evidence concerns the gene GSTM1 and anemia.