The level of phosphorylated cofilin is low in invasive cells of the leukemic Jurkat T cell line, cervical cancer HeLa, colon KM12, liver HepG2 and kidney COS1 cells (Nebl et al. 1996; Subramaniam et al. 2005; Yamaguchi et al. 2005). The gene discussed is CFL1; the disease is cervical carcinoma.