CFL1 and carcinoma: Moreover, the level of phosphorylated, inactive cofilin was reported to be decreased in cell lines derived from T cell lymphoma (Jurkat), carcinomas from the cervix (HeLa), colon (KM12), liver (HepG2), and kidney (COS1) (Nebl et al. 1996; Subramaniam et al. 2005; Yamaguchi and Condeelis 2007).