According to an IHC analysis of hPTTG1 and CXCR2 expression, we classified these primary IDCs and metastatic carcinomas into the following four groups: hPTTG1 (2+,3+)/CXCR2 (2+,3+); hPTTG1 (2+,3+)/CXCR2 (1+,0+); hPTTG1 (1+,0+)/CXCR2(2+,3+); and hPTTG1 (1+,0+)/CXCR2 (1+,0+). Here, CXCR2 is linked to metastatic carcinoma.