However, our findings indicate that elevated urinary VCAM-1 is not specific for SLE; rather, it appears to be a marker of renal injury, since the levels are also elevated in other types of inflammatory nephritis (for example, ANCA-GN) as well as nephropathies not typically associated with inflammation (for example, FSGS). This evidence concerns the gene VCAM1 and systemic lupus erythematosus.