Of the 51 patients, 26 had EGFR mutation, whereas the remaining 25 had wild-type EGFR. Significant associations of the EGFR mutation status were observed with sex (P = 0.036), tumor size (P = 0.017) and presence or absence of vascular invasion (P = 0.006), but not with age (P = 0.319), smoking status (P = 0.124), SUVmax on FDG-PET (P = 0.711) or tumor differentiation grade (P = 0.691) (Table 2). This evidence concerns the gene EGFR and neoplasm.