A different study reported that conditioned medium from BMDCs and plasma from paclitaxel-treated mice can promote metastatic properties in tumor cells in vitro by inducing matrix metalloproteinase-9 (MMP9), and paclitaxel treatment of mice with Lewis lung carcinoma led to accelerated MMP9-dependent metastases [125]. This evidence concerns the gene MMP9 and Carcinoma, Lewis Lung.