PPARG and bronchopulmonary dysplasia: It should be noted that BPD is thought to represent a failure of the developmental program, and therefore the signals and mechanisms involved in neonatal hyperoxic fibrosis may be different than the signals involved in fibrosis of fully differentiated adult lungs, and it would be interesting to study PPARγ-independent effects of electrophilic ligands of PPARγ in the neonatal animal models [91].