DNM1L and optic atrophy: OPA4 and OPA5: three families linked to the OPA4 or OPA5 loci present an optic atrophy that can not be differentiated from the phenotype observed in OPA1 patients: i.e. optic nerve pallor, decreased visual acuity, color vision defects, impaired VEP, and normal ERG and no extra-ocular findings[46,47].