Figure 4 illustrates these findings, by showing how MMP-9 levels reflect and track SRF accumulation in each patient. The correlation between MMP-9 levels and SRF accumulation may suggest a possible prognostic ability for MMP-9 in patients with AMD, and other retinal diseases affected by SRF accumulation. To further explore this idea, a ROC analysis was completed to test the capability of MMP-9 to detect differences between Group 1 and Group 2 (Figure 5). The gene discussed is MMP9; the disease is Abnormal retinal morphology.