MCRS1 and colorectal carcinoma: COX regression analysis indicated that high expression of MSP58 (P < 0.001), depth of invasion >pT1 (P = 0.008), distant organ metastasis (pM1) (P < 0.001), regional lymph node metastasis (≥pN1) (P < 0.001), and local recurrence (Yes) (P = 0.007) were independent, poor prognostic factors of CRC.