When all five risk factors (waist circumference, and concentrations of glucose, triglyceride and ALT, and platelet count) were combined, for established thresholds, the area under receiver operator curve (AUROC) value for incident fatty liver was 0.65 (95%CI 0.61, 0.69), with a positive predictive value (PPV) of 50.0% (95%CI 15.7, 84.3) and an NPV of 84.0% (95%CI 81.9, 86.0); whereas for the population-specific thresholds, the AUROC for incident fatty liver was 0.75 (95%CI 0.72, 0.78), with a PPV of 40.0% (95%CI 15.7, 84.3) and an NPV of 85.4% (95%CI 83.3, 87.3). Here, GPT is linked to fatty liver disease.