PODXL and serous adenocarcinoma: In that study, it was also demonstrated that forced expression of PODXL in serous ovarian carcinoma-derived OVCAR-3 cells resulted in localization of PODXL to the cell surface, decreased cell adhesion to mesothelial monolayers and diminished levels of β1-integrin, leading the authors to conclude that PODXL may facilitate transperitoneal metastasis of high grade serous carcinoma[13].