Routine use of oxytocin during the third stage of labor also significantly reduced the rate of PPH diagnosis by 75% in this setting (no prophylaxis: 29% (325/1624) vs. prophylaxis: 7% (50/727)); thus reducing the number of women requiring treatment with oxytocics and their exposure to any side effects from these drugs. The gene discussed is OXT; the disease is pulmonary arterial hypertension.