In our Han Chinese patients, the 5-year OS was 58% in ALK+ S-ALCL patients versus 36% in ALK- S-ALCL patients, which was lower than other reports showing 70%-80% survival in ALK+ versus 33%-49% in ALK- S-ALCL [6,7,31,32]. The gene discussed is ALK; the disease is anaplastic large cell lymphoma.