We found that some of the clinical features of ALK+ S-ALCL in our analysis were similar to those in Savage et al., but Chinese patients with ALK- S-ALCL are younger (median age 34 vs. 58), with a lower percentage of B symptoms (35 vs. 57%), and different sites and frequency of extranodal involvement, compared to those reported by Savage et al.[8]. The gene discussed is ALK; the disease is anaplastic large cell lymphoma.