Intestinal metaplasia samples also presented a higher frequency of hTERT (p = 0.001, OR = 1.8), MYC (p = 0.001, OR = 1.8), and p53 (p = 0.008, OR = 1.5) immunoreactivity compared to atrophic gastritis specimens. This evidence concerns the gene TP53 and chronic atrophic gastritis.