ERCC4 and cancer: As showed in Figure 2, a total of 88 published and unduplicated records from the MEDLINE and EMBASE databases, 17 records from the CNKI database and one submitted record were retrieved by using the key words mentioned in the Methods, of which 39 studies examined the association of the commonly studied XPF polymorphisms [i.e., rs1800067 (Arg415Gln, exon 8), rs1799801 (Ser835Ser, exon 11), rs2020955 (Ser662Pro, exon10) and rs744154 (intron 1); Figure 1B] with cancer risk.