ERCC4 and cancer: Furthermore, the subjects from Crew’s study of 1,018 breast cancer cases and 1,065 controls were predominantly of Caucasians [21], leading to a sample size of more than 2,000 Caucasians added to our new analysis, which increased the weight of Caucasians and study power, although we did not find evidence of any association between the XPF-rs1800067 SNP and overall risk of cancers, including breast cancer.