However, in stratification analyses, we found a significant association of the XPF-rs1799801 SNP with a reduced cancer risk in Caucasian populations, with a statistical power of 100% (4,845 cases and 5,556 controls; recessive model: OR = 0.87, 95% CI = 0.76–1.00, P = 0.049, P = 0.723 for heterogeneity test, I2 = 0; Table 2, Figure 4A, B). The gene discussed is ERCC4; the disease is cancer.