Anthrax intoxication begins when PA binds to CMG2 or TEM8 on the cell surface, prompting cleavage of PA by cell-surface proteases [36], oligomerization to a heptameric species, complex formation with the pathogenic toxin components, Lethal Factor (LF) and Edema Factor (EF) [37], and their subsequent delivery to the interior of the cell via endocytosis [38]–[40]. This evidence concerns the gene ANTXR2 and anthrax infection.