In experimental models of diabetes, it has been reported that RSV administration reduces reactive oxygen species [15] and the incidence of cardiomyocyte death [16]–[17], and improves cardiac function by enhancing the expression of sarcoplasmic calcium ATPase (SERCA2a) in cardiomyocytes, through the activation of deacetylase silent information regulator 2/sirtuin 1 (SIRT1) [18]–[19]. Here, SIRT1 is linked to diabetes mellitus.