Flavone A and flavone B cytotoxic activity is directed towards highly tumorigenic cells that express high levels of ALDH: Caco-2 and HCT-116 [34], [35], as well as pancreatic cancer Panc28 and MIA PaCa, [36], and breast cancer SK-BR3 [37] cells. The gene discussed is LDHA; the disease is pancreatic neoplasm.