When we investigated the combined effect of SNP haplotypes 1, 2 and, 3 and obesity (BMI, WC adjusted for HC, HC adjusted for WC) or the NFKB1 -94 ATTG ins/del polymorphism, the results showed no indication that haplotype carrier status modified the effect of the investigated variable. Here, NFKB1 is linked to obesity due to melanocortin 4 receptor deficiency.