HMOX1 and cancer: Recent findings support the key roles of the antioxidant response element (ARE) in regulating the expressions of some phase II and antioxidant enzymes such as heme oxygenase-1 (HO-1), glutathione S-transferase (GST), and NAD(P)H: quinine oxidoreductase 1 (NQO1) by phenolic antioxidants and other naturally occurring cancer chemopreventive agents [1,3].