Concerning plasma adipokine levels, there was an increase in plasma resistin of 38% (P < 0.05) at the end of week 4 but not at week 2 in the HF–HS diet group compared to the control group, whereas no difference in plasma adiponectin level was found between the control and the HF–HS groups at either time point. This evidence concerns the gene RETN and hydrops fetalis.