MYOF and breast carcinoma: In the current manuscript, we present novel data confirming the computational modeling and show, in addition, that MYOF-deficient MDA-MB-231 human breast cancer cells exhibit a more epithelial shape compared to the mesenchymal morphology of wild-type MDA-MB-231 cells, suggesting that some features of a mesenchymal-to-epithelial transition (MET) phenotype [31] may exist in the absence of functional MYOF protein.