CXCL8 and respiratory tract infectious disorder: First, lung inflammation-associated diseases in ruminants are very important in terms of economic loss for the beef meat industry; according to a report of the Committee for Animal Health Research Programs, major disease-related losses attributed to respiratory infections were calculated to be ∼400 million Euros per year; therefore the creation of an innovative in vivo platform for testing new respiratory anti-inflammatory drugs targeting specific pathways, such as IL-8, would be highly desirable.