IL-8 exerts a wide variety of actions on pulmonary disease pathophysiology in ruminants and human during bacterial or viral infection, acute respiratory distress syndrome (ARDS), reperfusion injury and transplantation, lung injuries due to physical and chemical conditions, allergic inflammation and asthma, idiopathic pulmonary fibrosis and other diffuse lung diseases, including lung cancer [2], [4]. This evidence concerns the gene CXCL8 and pulmonary fibrosis.