Evidence consistent with the hypothesized link comes from a study of patients with Parkinson's Disease (PD), the quintessential pathological condition of dopamine depletion: a strong association was reported between DBH and PD for the same SNP we examined, rs1611115, for the C allele of this SNP, consistent with an association with low dopaminergic function [34]. This evidence concerns the gene DBH and Parkinson disease.