The trimodal pattern of MPO expression observed in AMI patients was not detectable in any of the other conditions, regardless of: i) increased peripheral neutrophil count in patients with acute traumatic bone fracture (12.8±0.3 neutrophils/μL) and sepsis (22.2±4.4 neutrophils/μL); ii) the presence of ANCA, known to amplify the activation of neutrophils [12], and iii) the massive elevation in inflammatory markers of patients with giant cell arteritis, polymyalgia rheumatica or rheumatoid arthritis (Table 4). This evidence concerns the gene MPO and rheumatoid arthritis.