A positive correlation was identified for up-regulated COX-2 at 6 and 24 h after UV-C irradiation and an increased heat evoked erythema at 24 h (Pearsons r: 0.57; (6 h) and r:0.62; (24 h)) but after Bonferroni correction no significant difference was detected (fig. The gene discussed is PTGS2; the disease is Erythema.