Pre-incubation of cells with NAC completely blocked the effects of TS on expression of FOXM1 (Fig. 3A, lanes 6–10), activation of ERK1/2 (Fig. 3D, lane 6), and cell morphology (Fig. 3E), indicating that inhibition of FOXM1 expression by TS in MM cells is redox-dependent. This evidence concerns the gene MAPK3 and Miyoshi myopathy.