On day 7, the mRNA levels of the IL-6 were significantly lesser in the ivabradine group and carvedilol group compared with the myocarditis group (P<0.05; Figure 6), and ivabradine administration attenuated the increase in MCP-1 significantly (P<0.05) in the infected mice, but carvedilol had no effect on the MCP-1. Here, IL6 is linked to myocarditis.