Although CACS was significantly correlated with hs-cTn-I concentrations in both patients with RA (rho = 0.33, P<0.001) and control subjects (rho = 0.24, P = 0.005), there were no statistically significant associations after multivariable model adjustment for age, race, sex and FRS in both RA (P = 0.79) and control subjects (P = 0.43). The gene discussed is TNNI3; the disease is rheumatoid arthritis.