[20], [21] To test whether TEAD4 is present in neovascular complexes associated with AMD, antibodies raised against human TEAD4 were used in immunohistopathologic analysis of sections from eyes with neovascular AMD. Hematoxylin and eosin staining demonstrated subretinal neovascular membranes in the three globes obtained post-mortem from three patients with age-related macular degeneration. Endothelium of choroidal new blood vessels within the membrane stained positively for TEAD4 in two eyes (Figure 10); the third eye showed relatively weak staining overall. The gene discussed is TEAD4; the disease is age-related macular degeneration.