GCG and type 2 diabetes mellitus: Long-term exposure of type 2 diabetic patients to exenatide, an incretin mimetic agent, was not significantly associated to an increased bone fracture risk, despite the progressive weight loss: at 82 weeks an average weight reduction of 4.4 kg was reported, with a mean of 11.9 kg (−11.4% of baseline body weight) in highest weight loss quartile [35].