This is in line with studies in human, where a large number of mutations of Lamin A/C (LMNA) were found, causing a wide range of human disorders, including lipodystrophy, neuropathies, autosomal dominant Emery-Dreifuss muscular dystrophy (EDMD), and progeria. Here, LMNA is linked to autosomal dominant Emery-Dreifuss muscular dystrophy.