In particular, all seven AML-associated miRNAs, miR-125b, miR-126, miR-142-3p, miR-155, miR-223, miR-29a, and miR-29b, were predicted to regulate the most significant sub-network within the AML Signalisome containing AhR pathway signaling. This evidence concerns the gene AHR and acute myeloid leukemia.