We assessed the relationship between the plasma concentrations of CRP, PCT, and PSP/reg; the concentrations of inflammatory cytokines; the number of leukocytes; severity scores (APACHE II, SAPS II and III, and SOFA); and in-hospital mortality in patients with severe sepsis or septic shock (Table 3 and Additional file 1, Table S1). This evidence concerns the gene CRP and Sepsis.