Moreover, in contrast to IL-6 and PCT, the age-adjusted ORs (95% CIs) of mortality among patients with septic shock increased continuously across PSP/reg quartiles: PSP/reg OR 1.0 [reference group], 1.5 (0.19 to 10.0), 5.1 (0.8 to 32.0), and 6.4 (0.96 to 42.0), respectively (test for trend P = 0.02). The gene discussed is IL6; the disease is Shock.