Among tumor samples, HMGB1 expression was scored 1–2 in 13 (8.1%), 3–4 in 21 (13.0%), 6–8 in 58 (36.0%), 9–12 in 50 (31.1%) and 16 in 19 (11.8%) specimens. This evidence concerns the gene HMGB1 and neoplasm.