TTR and stroke disorder: Five model inputs were shown to be influential to the ICER of dabigratan 150 mg in one-way sensitivity analysis: (1) average TTR in genotype-guided AC, (2) utility of warfarin, (3) utility of dabigatran, (4) risk of stroke with dabigatran 150 mg versus warfarin and (5) stroke rate with warfarin when INR was in target range.