In details, the levels of GIP are lower in LC patients than in CHC patients whereas those of C-peptide, IL-1α, IL-2R, IL-12, IL-18, CXCL9, MIF, β-NGF, HGF and leptin are higher in LC patients than in CHC patients. This evidence concerns the gene CXCL9 and laryngotracheoesophageal cleft.