In CHC patients greater amounts of IL-1α, IL-2R, IL-12, IL-18, CXCL1, CXCL9, MIF, β-NGF, C-peptide, GIP, insulin, leptin, PAI-1, resistin, adiponectin and adipsin and lower of ghrelin were secreted with respect to healthy controls (Figures 1–2 and Table 2). This evidence concerns the gene IL1A and cryohydrocytosis.