On the other hand, the levels of CXCL1, β-NGF, resistin, adiponectin, adipsin and PAI-1 are similar in CHC and CHD patients whereas IL-1α, IL-2R, IL-12, IL-18, leptin, C-peptide, ghrelin and CXCL9 are higher in CHD patients than in CHC patients and GIP is lower in CHD patients than in CHC patients (with p-value <0.01). The gene discussed is LEP; the disease is cryohydrocytosis.