This analysis has evidenced that: i) in T2D patients IL-18, resistin and MIF correlated positively with glycemia and BMI levels, ii) in CHC patients IL-2R, MIF and β-NGF correlated positively with transaminase values, iii) in CHD patients IL-18 and C-peptide correlated positively with transaminase, BMI and glycemia values, iv) in LC patients CXCL1, CXCL9 and HFG correlated negatively with albumin values and v) in LCD patients glucagon and HGF correlated positively with BMI and glycemia values and negatively with albumin values. The gene discussed is IL18; the disease is type 2 diabetes mellitus.