IL17A and Hepatic fibrosis: To gain in vivo evidence of the Treg/Th17 balance during fibrosis progression, in this part we firstly established ConA-induced mouse liver fibrosis models (Figure7A) and found the frequencies of CD25+ and IL-17+ cells significantly increased in livers and spleens after ConA administrations (Figure 7B–D), which was similar with the increase of Treg and Th17 frequencies in CHB patients.