Of all the proteins identified, 294 were affected by expression of the NPM/ALK expression, 293, 105, 197 and 214 respectively by the myeloproliferative disorder oncogenes BCR/ABL, TEL/PDGFRβ, Kit D816V, and Fip1L/PDGFRα respectively, and 194 in the FLT3 ITD oncogene found in acute myeloid leukaemia (see table S3 for the list of proteins that change as a consequence of oncogene expression). The gene discussed is ALK; the disease is acute myeloid leukemia.