EGFR and neoplasm: Cetuximab (Erbitux) is a chimeric IgG1 monoclonal antibody that competitively inhibits transforming growth factor-α (TGF-α) ligand from binding to epidermal growth factor receptor (EGFR), resulting in inhibition of tumour growth, invasion and metastasis, DNA damage repair and angiogenesis [4], [5], [6].