CDKN2A and lymphoma: Specific genetic and epigenetic factors play a role in the pathogenesis of many lymphomas, including translocations (i.e. API2-MALT1CCND1-IGH)[14], defects in tumor suppressor genes (i.e. RB1TP53p15/CDKN2B)[15-19], and promoter hypermethylation of tumor suppressor genes (i.e. p16/CDKN2A)[20-22].